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KMID : 0367320050160010124
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Journal of the Korean Academy of Child and Adolescent Psychiatry
2005 Volume.16 No. 1 p.124 ~ p.131
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ANTIDEPRESSANT INDUCED-MANIC EPISODE IN ADOLESCENTS WITH PRECEDING ANXIETY SYMPTOMS
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Chungh Dong-Seon
Kim Jeong-Hyun
Ha Kyoo-Seob
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Abstract
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Childhood and adolescent onset-bipolar disorders have higher rate of comorbidity with anxiety disorders as well as attention deficit hyperactivity disorder and conduct disorder. Obsessive compulsive disorder, social phobia, panic disorder, and separational anxiety disorder are common comorbid anxiety disorders with bipolar disorders in child and adolescent. Prospective and reliable data on temporal and causal relationship between the onset of bipolar disorders and the onset of comorbid anxiety disorders are still in debate. The authors report 2 adolescent cases with antidepressant induced-manic episodes with preceding anxiety symptoms. The authors suggest careful prescription of antidepressants for anxiety disorders, even for those who do not have definite past history or family history of bipolar disorders. Further comprehensive and prospective studies are requested for the temporal relationship and pharmacological guideline for comorbid bipolar disorders and anxiety disorder in child and adolescent.
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KEYWORD
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Bipolar disorder, Anxiety disorder, Adolescent, Antidepressant
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